NBDE Part II Pharmacology MCQ With Answer Key

Question 16: Which of the following substances mechanisms are based on interaction with ion channels

A. Sodium channel blockers

B. Calcium channel blockers

C. Potassium channels activators

D. All of the above

Answer & Explanation Answer: [D]

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Question 17: Which of the following statements about efficacy and potency is INCORRECT?

A. The ED50 is a measure of drug’s efficacy

B. Efficacy is usually a more important clinical consideration than potency

C. Efficacy is the maximum effect of a drug

D. Potency is a comparative measure, refers to the different doses of two drugs that are needed to produce the same effect

Answer & Explanation Answer: [A]

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Question 18: What do you mean by  Therapeutical Dose:

A. The amount of a substance to produce the minimal biological effect

B. The amount of a substance to produce effects hazardous for an organism

C. The amount of a substance to produce the required effect in most patients

D. The amount of a substance to accelerate an increase of concentration of medicine in an organism.

Answer & Explanation Answer: [C]

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Question 19: What does term “Tachyphylaxis” mean:

A. A drug interaction between two similar types of drugs

B. Very rapidly developing tolerance

C. A decrease in responsiveness to a drug, taking days or weeks to develop

D. None of the above

Answer & Explanation Answer: [B]

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Question 20: Development of tolerance towards a drug is due to:

A. Rapid excretion of a drug

B. Diminished absorption

C. Both of the above

D. None of the above

Answer & Explanation Answer: [D]

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